About Centene
Centene Corporation is headquartered in St. Louis, Missouri. Its first health plan began operating in Wisconsin in 1984. The company focuses on government-sponsored and subsidized coverage and works through local, state-based health plans.
Brands and products
- Medicaid — Centene describes itself as the largest Medicaid health insurer in the country.
- Ambetter Health — individual plans on the Health Insurance Marketplace; Centene is the largest Marketplace carrier.
- Wellcare — Medicare Advantage plans, plus Medicare Part D prescription drug plans.
As of December 31, 2025, Centene had 12.5 million Medicaid members in 30 states, 5.5 million Marketplace members in 29 states and 1.0 million Medicare Advantage members across 32 states. Benefits, networks and plan names vary by state.
Contacts
Centene directs members to the phone number of their state health plan; its corporate line, 314-725-4477, is for corporate inquiries only. Learn more in our health insurance guide or request a quote.